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. 2017 Aug 15;9(8):3696–3704.

Figure 5.

Figure 5

Knockdown of UCA1 suppressed the neural stem cell proliferation and inhibited the neural stem cell differentiation into neuron through targeting Hes1. A. The expression of UCA1 was upregulated in the neural stem cell after treated with pcDNA-Hes1. B. The protein expression of Hes1 was measured by Western blot. C. Ectopic expression of Hes1 could impair siUCA1-induced neural stem cells proliferation. D. Overexpression of Hes1 suppressed siUCA1-induced β-tubulin III mRNA expression. E. Overexpression of Hes1 suppressed siUCA1-induced β-tubulin III protein expression. F. Overexpression of Hes1 suppressed siUCA1-induced GFAP mRNA expression. G. Overexpression of Hes1 suppressed siUCA1-induced GFAP protein expression. *P<0.05, **P<0.01 and ***P<0.001.