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. 2017 Aug 29;7:9609. doi: 10.1038/s41598-017-09805-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of the ABR data from P0–1 injected and control mice. (a) Representative ABR traces recorded from injected (high and low titer) mice 4wks after AAV2/9 inoculation at P0-1 (high and low dose) and the control 4-wk-old mice. Waveforms from injected and control mice appear similar. (b) Click and tone-burst ABRs show relatively normal threshold profiles in the injected mice compared with control mice at 4wks (n, numbers of ears). Slight differences of ABR threshold of less than 10 dB were observed across all frequencies. Data are means ± SEM.