Table III.
Adjusted OR of factors associated with LVEF < 50% using multiple logistic regression analysis
| Variables | OR (95% CI) | P-value | Variables | OR (95% CI) | P-value | |
|---|---|---|---|---|---|---|
| Model 1: | Model 2: | |||||
| Age [years] | 0.993 (0.964–1.022) | 0.628 | Age [years] | 0.992 (0.963–1.022) | 0.588 | |
| Male (1 = yes, 0 = no) | 3.996 (1.800–8.868) | 0.001 | Male (1 = yes, 0 = no) | 3.681 (1.666–8.135) | 0.001 | |
| Serum creatinine [μmol/l] | 1.004 (1.000–1.008) | 0.055 | Serum creatinine [μmol/l] | 1.004 (1.000–1.008) | 0.036 | |
| HDL-C [mmol/l] | 0.784 (0.283–2.170) | 0.639 | HDL-C [mmol/l] | 0.715 (0.257–1.990) | 0.521 | |
| LDL-C [mmol/l] | 0.980 (0.689–1.394) | 0.910 | LDL-C [mmol/l] | 0.963 (0.676–1.371) | 0.834 | |
| Hemoglobin [g/l] | 1.006 (0.987–1.026) | 0.528 | Hemoglobin [g/l] | 1.007 (0.988–1.027) | 0.468 | |
| Lp(a) [g/l]: | 5.566 (1.745–17.758) | 0.004 | Lp(a): | – | 0.030 | |
| – | Quartile 1 | Reference | ||||
| – | Quartile 2 | 1.487 (0.560–3.951) | 0.426 | |||
| – | Quartile 3 | 2.746 (1.083–6.963) | 0.033 | |||
| – | Quartile 4 | 3.234 (1.290–8.105) | 0.012 | |||
HDL-C – high-density lipoprotein cholesterol, LDL-C – low-density lipoprotein cholesterol, Lp(a) – lipoprotein(a), HbA1c – glycated hemoglobin. Lp(a) entered the regression equation as a continuous variable (g/l) in model 1. Lp(a) quartiles also entered the regression equation as a categorical variable in model 2 (quartile 1 as reference).