Table I.
Demographic and clinical variables. Differences between patients (SG) and control group (CG)
| Variable | CG (n = 182) | SG (n = 163) | P-value |
|---|---|---|---|
| Age [years]a | 70 (66–71) | 71 (70–76) | < 0.0001 |
| BMI (Quetelet index [kg/m2])a | 24 (23–24.5) | 24 (23–24.5) | 0.8073 |
| Further educationa (years of education above 8th grade) | 7 (4–8) | 4 (3–4) | < 0.0001 |
| Current smokers (%)b | 15.38 [10.44–21.43] | 36.20 [28.84–44.17] | < 0.0001 |
| Alcohol consumption (%)b: | |||
| Occasional | 12.64 [8.25–18.13] | 14.72 [9.82–20.86] | 0.5743 |
| Moderate | 6.04 [2.75–10.44] | 5.52 [2.46–10.43] | 0.8366 |
| Daily | 1.10 [0.003–3.84] | 2.45 [0.62–6.13] | 0.3387 |
| FT4 [ng/dl]a | 1.2 (1.1–1.4) | 1.2 (1.1–1.35) | 0.8166 |
| NOx [μmol/l]a | 43.78 (40.66–55.21) | 98 (82–101.23) | < 0.0001 |
| MMSE [points]a | 30 [29–30] | 22 [21–24] | < 0.0001 |
| MMSE-PCA [points]a | 6 [6–6] | 2 [1–3] | < 0.0001 |
| KS [points]b: | |||
| 0 | 95.05 [90.66–97.80] | 0.00 [0.00–2.45] | < 0.0001 |
| 1 | 4.95 [2.20–9.34] | 25.77 [19.02–33.12] | < 0.0001 |
| 2 | 0.00 [0.00–2.20] | 38.04 [30.68–46.01] | < 0.0001 |
| 3 | 0.00 [0.00–2.20] | 36.20 [28.84–44.17] | < 0.0001 |
BMI – body mass index
a
median (Q1–Q3), Q1 = 25th percentile; Q3 = 75th percentile; Mann-Whitney test.
b
% [95% CI], CI = confidence interval [lower bound–upper bound]; Z test for proportions.