Table I.
Baseline characteristics of the study population
| Parameter | All(N = 285) | Group 1 (n = 81) | Group 2 (n = 62) | Group 3 (n = 62) | Group 4(n = 80) | P-value* |
|---|---|---|---|---|---|---|
| Age [years] | 58.9 ±14.1 | 57.9 ±14.9 | 62.0 ±14.0 | 55.4 ±13.9 | 60.1 ±13.2 | 0.06 |
| Weight [kg] | 71.3 ±14.7 | 75.4 ±13.9 | 70.7 ±16.3 | 70.1 ±12.9 | 68.6 ±14.9 | 0.02 |
| Dialysis vintage [years] | 52.6(18.7–97.5) | 27.8(11.3–62.2) | 51.6(17.0–93.5) | 81.5(22.7–147.2) | 72.8(37.2–117.4) | < 0.001 |
| Male, n (%) | 136 (47.7) | 35 (43.2) | 25 (40.3) | 37 (59.7) | 39 (48.8) | 0.13 |
| Hypertension, n (%) | 213 (74.7) | 56 (69.1) | 50 (80.6) | 47 (75.8) | 60 (75.0) | 0.47 |
| Systolic pressure [mm Hg] | 134.9 ±14.9 | 135.1 ±14.5 | 137.1 ±13.4 | 133.7 ±15.1 | 134.2 ±15.2 | 0.57 |
| Diastolic pressure [mm Hg] | 70.7 ±10.9 | 70.1 ±12.5 | 70.7 ±10.2 | 72.6 ±10.9 | 70.1 ±10.0 | 0.51 |
| Diabetes, n (%) | 50 (17.5) | 15 (18.5) | 11 (17.7) | 11 (17.7) | 13 (16.3) | 0.99 |
| NYHA class 3–4, n (%) | 15 (5.3) | 1 (1.2) | 4 (6.5) | 2 (3.2) | 8 (10.0) | 0.07 |
| Peripheral arterial disease, n (%) | 45 (15.8) | 13 (16.0) | 13 (21.0) | 5 (8.1) | 14 (17.5) | 0.24 |
| Coronary artery disease, n (%) | 50 (17.5) | 12 (14.8) | 13 (21.0) | 6 (9.7) | 19 (23.8) | 0.13 |
| Stroke, n (%) | 25 (8.8) | 5 (6.2) | 5 (8.1) | 8 (12.9) | 7 (8.8) | 0.57 |
| Anuric, n (%) | 152 (53.3) | 36 (44.4) | 38 (61.3) | 36 (58.1) | 42 (52.5) | 0.19 |
| NT-proBNP [pg/ml] | 4595.0(1826.5–13342.0) | 1615.0(1052.0–3331.5) | 8684.5(5627.5–16691.0) | 2016.5(1007.7–2780.0) | 18944.0(8206.6–30109.3) | < 0.001 |
| Hemoglobin [g/dl] | 11.5 ±1.5 | 11.3 ±1.5 | 11.5 ±1.5 | 11.6 ±1.4 | 11.5 ±1.6 | 0.73 |
| CRP [mg/dl] | 5.3(2.1–12.3) | 4.2(2.1–8.5) | 8.4(3.3–17.1) | 4.7(1.4–13.1) | 5.8(1.8–12.7) | 0.04 |
| Albumin [g/dl] | 3.9 ±0.3 | 3.9 ±0.2 | 3.8 ±0.3 | 3.9 ±0.3 | 3.9 ±0.3 | 0.24 |
| Calcium [mg/dl] | 8.6 ±0.7 | 8.5 ±0.6 | 8.5 ±0.7 | 8.6 ±0.7 | 8.6 ±0.7 | 0.47 |
| Phosphate [mg/dl] | 5.1(3.9–6.2) | 5.2(4.1–6.4) | 5.3(4.6–6.3) | 4.9(3.3–6.6) | 4.7(3.5–5.8) | 0.11 |
| TBW [l] | 33.9 ±6.3 | 33.7 ±6.2 | 33.0 ±6.4 | 35.7 ±6.8 | 33.8 ±5.9 | 0.09 |
| ECW [l] | 16.2 ±2.9 | 15.8 ±2.6 | 15.3 ±2.9 | 17.2 ±3.1 | 16.4 ±2.8 | 0.001 |
| ICW [l] | 17.8 ±3.7 | 17.9 ±3.9 | 17.7 ±3.7 | 18.5 ±3.9 | 17.3 ±3.3 | 0.32 |
| AFO [l] | 1.2 ±1.3 | 0.3 ±0.7 | 0.1 ±0.8 | 2.3 ±1.1 | 2.1 ±0.8 | < 0.001 |
| RFO, % | 7.1 ±7.6 | 1.6 ±4.2 | 0.8 ±5.8 | 13.4 ±5.1 | 12.8 ±4.3 | < 0.001 |
Data are expressed as mean ± SD, median with IQR, or percent frequency, as appropriate. AFO – absolute fluid overload, CRP – C-reactive protein, ECW – extracellular water, ICW – intracellular water, NT-proBNP – N-terminal pro-B-type natriuretic peptide, NYHA – New York Heart Association, RFO – relative fluid overload, TBW – total body water.
*
Comparison between groups