Table II.
Univariable COX analysis for all-cause mortality
| Parameter | HR | 95% CI | P-value |
|---|---|---|---|
| NT-proBNP – RFO Groups: | |||
| Group 1 | Reference | ||
| Group 2 | 1.45 | 0.75–2.82 | 0.27 |
| Group 3 | 1.55 | 0.81–2.96 | 0.19 |
| Group 4 | 2.36 | 1.32–4.23 | 0.004 |
| Log NT-proBNP [pg/ml]* | 1.48 | 1.19–1.83 | < 0.001 |
| RFO (%) | 1.03 | 1.01–1.06 | 0.02 |
| Age [years] | 1.04 | 1.02–1.06 | < 0.001 |
| Diabetes (0 – no, 1 – yes) | 1.56 | 0.95–2.54 | 0.08 |
| Gender (1 – male, 2 – female) | 0.69 | 0.45–1.05 | 0.08 |
| Severe NYHA Class (0 – Class 1 and 2, 1 – Class 3 and 4) | 3.87 | 2.05–7.28 | < 0.001 |
| Hemoglobin [g/dl] | 1.18 | 1.03–1.35 | 0.02 |
| Log CRP [mg/dl]* | 1.40 | 1.13–1.74 | 0.002 |
| Log phosphorus [mg/dl]* | 0.80 | 0.69–0.92 | 0.002 |
CRP – C-reactive protein, NT-proBNP – N-terminal pro-B-type natriuretic peptide, NYHA – New York Heart Association, RFO – relative fluid overload.
*
Hazard ratio for each increase in 1 SD in log of the variable.