Table III.

Multivariable COX analysis for all-cause mortality (using NR-proBNP – RFO Groups)

Parameter	HR	95% CI	P-value
NT-proBNP – RFO Groups:
Group 1		Reference
Group 2	1.16	0.59–2.26	0.67
Group 3	1.40	0.72–2.75	0.32
Group 4	2.00	1.11–3.62	0.02
Age [years]	1.04	1.02–1.06	< 0.001
Diabetes (0 – no, 1 – yes)	1.02	0.62–1.69	0.94
Gender (1 – male, 2 – female)	0.76	0.49–1.18	0.76
Severe NYHA Class (0 – Class 1 and 2, 1 – Class 3 and 4)	2.04	1.06–3.95	0.03
Hemoglobin [g/dl]	1.22	1.06–1.39	0.004
Log CRP [mg/dl]*	1.30	1.03–1.64	0.03
Log phosphorus [mg/dl]*	0.83	0.69–0.99	0.04

CRP – C-reactive protein, NT-proBNP – N-terminal pro-B-type natriuretic peptide, NYHA – New York Heart Association, RFO – relative fluid overload.

^*Hazard ratio for each increase in 1 SD in log of the variable.