Table 4.
Characteristics of children with idiopathic nephrotic syndrome studied.
| Value | |
|---|---|
| Patient characteristics | |
| Number of patients | 42 |
| Sex ration (M/F) | 30/12 |
| Age (years) | 12 [9–15] |
| Body weight (kg) | 36.4 [27.9–54] |
| Daily MMF dose (mg/m2) | 1175 [1134–1259] |
| CsA co-medication (n=15) | |
| Number of samples | 18 |
| CsA dose (mg/day) | 140 [105–195] |
| CsA trough concentration (µg/L) | 89 [67–130] |
| CsA AUC0–12 h (µg.h/L) | 2823 [1391–4163] |
| Biological values | |
| Serum protein (g/L) | 65 [63–68.8] |
| Serum albumin (g/L) | 40.2 [38–45] |
| Serum creatinine (µmol/L) | 51 [31–111] |
| Urine protein: creatinine ratio (mg/mmol) | 8 ratios>30 mg/mmol |
NOTE: Values are expressed as median and interquartile range.
Abbreviations: AUC: area under the curve, CsA, ciclosporin; MMF, mycophenolate mofetil