Table 3.
EORTC QLQ-C30a + tingling hands or feet and HADSb mean scores of patients, a lymphoma reference cohort, and a normative population, and clinically important differences between these groups.
| Measure | Patients (n=45) | Lymphoma reference cohort (n=876) | Normative population (n=1852) | Patients vs lymphoma cohort | Patients vs normative population | |||
| P valuec | Clinical relevance | P valuec | Clinical relevance | |||||
| EORTC QLQ-C30, mean (SD) | ||||||||
| Physical functioning | 83.1 (20) | 79.4 (21) | 90.5 (15) | .21 | No | <.001 | Small | |
| Emotional functioning | 82.2 (21) | 82.8 (21) | 87.9 (17) | .86 | No | .02 | Trivial | |
| Cognitive functioning | 80.4 (22) | 82.4 (23) | 92.5 (14) | .57 | No | <.001 | Medium | |
| Social functioning | 85.9 (25) | 84.4 (24) | 93.6 (16) | .68 | No | .002 | Small | |
| Global health status/QoLd | 73.3 (20) | 74.0 (20) | 77.6 (17) | .82 | No | .10 | Small | |
| Fatigue | 24.7 (23) | 28.9 (27) | 17.0 (20) | .30 | No | .01 | Small | |
| Tingling hands or feet | 18.5 (28) | 17.0 (29) | N/Ae | .73 | No | N/A | N/A | |
| HADS, mean (SD) | ||||||||
| Anxiety | 4.0 (3.8) | 4.4 (3.8) | 3.6 (3.2) | .51 | No | .34 | No | |
| Depressive symptoms | 3.9 (3.8) | 4.7 (3.8) | 3.6 (3.2) | .17 | No | .54 | No | |
aEORTC QLQ-C30: European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30.
bHADS: Hospital Anxiety and Depression Scale.
cP value is adjusted for age and sex.
dQoL: quality of life.
eN/A: not available.