Table 2.
3‐point bending analysis of 6‐week‐old male and female fl/fl and cKO mice (n = 4/genotype/sex)
| Sex | Maximum load (N) | Deflection at maximum load (mm) | Work to maximum load (J) | Stiffness (N/m) | Load at rupture (N) | Deflection at rupture (mm) | Work to rupture (J) | |
|---|---|---|---|---|---|---|---|---|
| M | fl/fl | 5.81 ± 0.65 | 0.60 ± 0.09 | 0.002 ± 0.00 | 17.7 ± 0.66 | 4.06 ± 0.45 | 0.80 ± 0.14 | 0.003 ± 0.00 |
| cKO | 5.95 ± 0.26 | 0.78 ± 0.14 | 0.002 ± 0.00 | 16.4 ± 0.97 | 4.22 ± 0.19 | 1.08 ± 0.16 | 0.004 ± 0.00 | |
| F | fl/fl | 4.58 ± 0.34 | 0.66 ± 0.04 | 0.002 ± 0.00 | 12.6 ± 1.42 | 3.21 ± 0.24 * | 0.90 ± 0.02 | 0.002 ± 0.00 |
| cKO | 5.30 ± 0.51 | 0.68 ± 0.06 | 0.002 ± 0.00 | 19.1 ± 1.44 ** | 3.88 ± 0.36 | 0.96 ± 0.11 | 0.003 ± 0.00 |
Data are represented as mean ± SEM.
*
p < 0.05 in comparison to male equivalent genotype.
**
p < 0.01 in comparison to female fl/fl. Data are represented as mean ± S.E.M.