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. 2017 Jun 27;23(40):9577–9584. doi: 10.1002/chem.201700747

Table 2.

The K d and thermodynamic values determined by ITC for all peptide–TLE1 binding experiments.

N1 K d1 [nm] ΔH1 [kcal mol−1] TΔS1 [kcal mol−1] N2 K d2 [nm] ΔH2 [kcal mol−1] TΔS2 [kcal mol−1]
MWRPW 0.24±0.001 3.5±1.9 −12.8±0.2 1.3 0.6±0.004 772±7.1 −11.1±0.11 2.72
FWRPW 0.18±0.002 8.6±3.9 −20.5±3.7 9.2±3.8 0.7±0.004 79.4±24.6 −14.6±0 4.6±0.2
18 0.18±0.01 24.7±24.2 −16.9±0 6.4±0.6 0.8±0.01 522±39.6 −11.8±1.8 3.2±1.7