Figure 2.

Prospective results from real‐world signal detection in VigiBase using vigiRank (upper section), compared to performance observed historically with disproportionality analysis (lower section). The reported P value was obtained using Fisher's exact test. Note that, unfortunately, information on labelledness and decisions to keep under review could not be reliably retrieved for the historical comparison period. IC, Information Component. [Color figure can be viewed at wileyonlinelibrary.com]