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. 2017 May 22;34(8):1145–1153. doi: 10.1111/dme.13358

Figure 2.

Figure 2

Islet cell antibody prevalence of glutamic acid decarboxylase (GAD) and/or islet antigen 2 (IA2) antibodies in relation to age of disease onset. (a) White European (linear regression slope= ‐0.38±0.03) and (b) ethnic Asian (linear regression slope= ‐0.012±0.05) participants with increasing age of onset. Distribution box plots showing antibody titre distribution in participants with increasing age of onset: (c) GAD antibodies in white European participants (P<0.001) and (d) IA2 antibodies in white European participants (P=0.096; non‐significant) in comparison with (e) GAD antibodies in the Singapore cohort (P=0.534; non‐significant) and (f) IA2 antibodies in the Singapore cohort (P= 0.399; non‐significant). Total population in each age group=100%. P values compared with cohort in 20–29‐year age group using one‐way anova. DK units, arbitrary National Institute of Diabetes and Digestive and Kidney Diseases units.