Figure 1.

Corticosterone (CORT) pretreatment exacerbates diisopropyl fluorophosphate (DFP)‐induced neuroinflammation. Effects of DFP exposure (4 mg/kg, i.p.) with and without prior CORT treatment (400 mg/L, 1.2% EtOH) on neuroinflammation as measured by qPCR of inflammatory cytokines and chemokines at 6 h post‐DFP. Tumor necrosis factor‐alpha (TNFα), IL‐6, (C–C) chemokine ligand 2 (CCL2), IL‐1b, leukemia inhibitory factor (LIF), and oncostatin M (OSM) were measured in cortex (left panels) and hippocampus (right panels). Data represents mean ± SEM (N = 4–6 mice/group). Statistical significance of at least p ≤ 0.05 is denoted by * compared to relevant control (vehicle or CORT) and # compared within treatment (saline or DFP).