Figure 6.

Neuroactive AChE inhibitors significantly reduce AChE activity in the brain, an effect that is reversed by corticosterone (CORT) diisopropyl fluorophosphate (DFP) and CORT chlorpyrifos oxon (CPO). AChE activity was measured in one brain hemisphere 30 min following AChE inhibitor exposure [DFP, CPO, pyridostigmine bromide (PB), and physostigmine (PHY)] with or without CORT pretreatment (400 mg/L, 1.2% EtOH). Data represents mean % ± SEM (N = 4–6 mice/group). Statistical significance of at least p ≤ 0.05 is denoted by * compared with relevant control (vehicle or CORT) and # compared with treatment (saline or AChE inhibitor).