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. 2017 Aug 16;8(8):194. doi: 10.3390/genes8080194

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Distribution of the Fragile X Mental Retardation 1 (FMR1) and FMR2 triplet repeats in primary ovarian insufficiency (POI) patients and controls; (A) Repeat distribution for the FMR1 gene. The modal number of CGG repeats was 30 (patients 91/258, controls 64/162), followed by 29 (patients 83/258, controls 35/162); (B) Repeat distribution for the FMR2 gene. The most frequent number of repeats was 15 among patients (53/245) as well as among controls (51/161), followed by 18 (patients 50/245, controls 29/161). Only non-related alleles were considered.