Table 3.

Results from the NCI-60 human tumor cell line five-dose assay for compounds 1–4. GI50, TGI, and LC50 values are given in μM concentrations.

Cell Line	1			2			3			4
	GI50	TGI	LC50	GI50	TGI	LC50	GI50	TGI	LC50	GI50	TGI	LC50
A549/ATCC	3.81	21.3	66.1	2.59	13.9	57.9	2.67	12.1	60.3	1.67	3.24	n/a
EKVZ	2.32	17.1	52.4	0.766	5.55	35.8	1.71	11.4	60.5	1.35	3.47	n/a
HOP-62	1.60	8.35	45.3	1.42	3.65	9.36	1.26	2.80	6.19	1.29	2.75	n/a
HOP-92	0.673	3.64	26.4	0.338	1.77	1.77	0.863	2.66	7.58	0.844	2.35	n/a
NCI-H226	1.85	10.4	64.1	1.08	3.82	3.82	1.31	3.92	> 100	1.35	2.93	n/a
NCI-H23	0.717	2.93	10.4	0.396	2.02	2.02	0.521	2.51	9.77	0.793	2.31	5.85
NCI-H322M	2.46	10.4	32.9	2.12	6.71	6.71	1.96	6.00	23.8	1.38	2.75	5.48
NCI-H460	1.59	10.7	44.0	0.724	2.15	2.15	1.22	3.01	7.44	1.25	2.82	n/a
NCI-H522	0.256	1.81	6.72	0.303	1.44	1.44	0.378	1.68	4.92	0.491	1.89	n/a