. Author manuscript; available in PMC: 2017 Dec 1.

Published in final edited form as: Clin Breast Cancer. 2016 Aug 1;16(6):487–493. doi: 10.1016/j.clbc.2016.07.013

Table 3.

Cardiac Risk Factors

	No Trastuzumab (n = 116)	Trastuzumab (n = 128)	P Value
	N (%)	N (%)	P Value
Baseline LVEF, median	67%	68%
BMI, kg/m² median (range)	25.5 (16.9–42.7)	27.3 (18.2–57.5)	.17
Creatinine clearance, mL/min median (range)	68.4 (32.2–156)	64.9 (28.4–146.2)	.11
Ever smoker	52 (45)	61 (48)	.7
Hypertension	57 (49)	57 (45)	.47
Hyperlipidemia	35 (30)	54 (42)	.05
Atrial fibrillation	5 (4)	4 (3)	.62
Diabetes mellitus	8 (7)	20 (16)	.03
Prior myocardial infarct reported	2 (2)	3 (2)	.73
Prior cerebrovascular event reported	3 (3)	3 (2)	.90
Prior history HF reported	2 (2)	3 (2)	.73

Abbreviations: BMI = body mass index; HF = heart failure; LVEF = left ventricular ejection fraction.