Table 2.

Light and Dark Cycles of Metabolic Parameters

Group	LIGHT				DARK
Male	FI (g)	EE (kcal/h)	X Counts	RER (VCO2/VO2)	FI (g)	EE (kcal/h)	X Counts	RER (VCO2/VO2)
C57Bl6	1.43 ± 0.196	0.366 ± 0.010	7398 ± 963	0.886 ± 0.005	3.07 ± 0.271	0.445 ± 0.009	24858 ± 3432	0.942 ± 0.009
[Tg(CAT)+/−]	1.34 ± 0.042	0.442 ± 0.008b#	9581 ± 2770	0.871 ± 0.006	2.64 ± 0.208	0.509 ± 0.009a*	24392 ± 4911	0.920 ± 0.009
Bob-Cat	1.35 ± 0.042	0.422 ± 0.010	5088 ± 1209	0.899 ± 0.010	2.98 ± 0.247	0.508 ± 0.008a*	17000 ± 3340	0.952 ± 0.009
Ob/Ob	1.04 ± 0.146	0.503 ± 0.013b$, d*#	874.4 ± 112.4a*#	0.867 ± 0.014	3.10 ± 0.444	0.589 ± 0.015a*, b#$	2421 ± 243.7a$, b#, c*	0.913 ± 0.016
Female
C57Bl6	1.78 ± 0.137	0.398 ± 0.019	4791 ± 405	0.924 ± 0.015	2.82 ± 0.109	0.453 ± 0.017	17357 ± 1136	0.939 ± 0.024
[Tg(CAT)+/−]	1.67 ± 0.140	0.362 ± 0.020	4502 ± 910	0.932 ± 0.022	2.97 ± 0.137	0.421 ± 0.022	14556 ± 3845	0.973 ± 0.017
Bob-Cat	1.74 ± 0.218	0.387 ± 0.017	11206 ± 2440	0.891 ± 0.010	2.80 ± 0.323	0.477 ± 0.021	40300 ± 8352a*#	0.910 ± 0.008

Light and Dark Cycles of Metabolic Parameters measured by CLAMS Technology: Male and female averaged light and dark cycles of food intake (FI) as average grams (g) of chow consumed per cycle, metabolic energy expenditure (EE) as average kcal/h of each mouse group, counts of physical movement as x ambulatory movement/cycle (X Counts), and average Respiratory Exchange Ratio (RER) as VCO₂/VO₂ per cycle. One-Way ANOVA was performed using Graph-Pad Prism 7. Data are represented as mean +/− SEM and significant differences are displayed with letters indicating p values:

^ap<0.05,

^bp<0.01,

^cp<.001,

^dp<.0001; symbols represent significant differences between genotypes,

^*compared to C57Bl6,

^#compared to [Tg(CAT)^+/−],

^$compared to Bob-Cat.