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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Biochim Biophys Acta. 2017 Jun 20;1863(9):2293–2306. doi: 10.1016/j.bbadis.2017.06.016

Table 4.

Key Characteristics of the Novel “Stress-Less” Bob-Cat Mouse

Male Characteristics
Female Characteristics

  • Lean mass +

  • Metabolic energy expenditure +

  • Catalase mRNA in adipose tissue +

  • Catalase enzymatic activity trend +

  • Oxidative stress in adipose tissue trend -

  • Leptin mRNA in adipose tissue ++++

  • Adiponectin mRNA in adipose tissue +

 Bob-Cat

  • Adipose weight +

  • Lean mass +

  • Physical activity trend +

  • Catalase protein expression trend +

  • Enzymatic activity in adipose tissue trend +

  • Leptin mRNA in adipose tissue +

  • Adiponectin mRNA in adipose tissue +

Bob-Cat Mouse Model Key Characteristics: Bob-Cat genotype compared to C57Bl6 mice increase depicted as (+). Significance represented as p<0.05 +, p<.0001 ++++