REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
anti-digoxigenin-POD, Fab fragments	Roche	Ref# 11 207 733 910; RRID: AB_514500
anti-fluorescein-POD, Fab fragments	Roche	Ref# 11 426 346 910; RRID: AB_840257
anti-DNP-HRP conjugate	Perkin-Elmer	Cat# FP1129; RRID: AB_2629439
mouse anti-BrdU	Becton Dickinson	Cat# 347580; RRID: AB_10015219
goat anti-mouse-HRP	Invitrogen	Cat# G-21040; RRID: AB_2536527
rabbit monoclonal anti-phospho-Histone H3 (Ser10)	Millipore	Cat# 04-817; RRID: AB_1163440
goat anti-rabbit-HRP	Invitrogen	Cat# G-21234; RRID: AB_2536530
Critical Commercial Assays
ApopTag Red In Situ Apoptosis Detection Kit	Millipore	Cat# S7165
Experimental Models: Organisms/Strains
Schmidtea mediterranea, clonal strain CIW4, asexual	Laboratory of Peter Reddien	Sánchez Alvarado et al., 2002
Oligonucleotides
Sequences used for all FISH probes and dsRNA provided in Table S2
Software and Algorithms
Image J (FIJI)	Schindelin et al., 2012	https://fiji.sc
ZEN digital imaging software	Zeiss	https://www.zeiss.com/microscopy/us/products/microscope-software/zen.html
GraphPad Prism	GraphPad Software	https://www.graphpad.com/scientific-software/prism/