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. 2017 Aug 29;18:93. doi: 10.1186/s12881-017-0450-3

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Genetic trees of the informative β-thalassemia families studied. a The analysis of the transmission of the −158 XmnI Gγ-globin and +25 Aγ-globin gene sequences from the parents to the studied β-thalassemia patients allowed to determine the linkage to the β⁰39 mutation. b, c Most frequent XmnI Gγ-globin and +25 Aγ-globin genes linked to β⁰39 (b) and β⁺IVSI-110 (c) globin genes. The comparative analysis does not include Fe11 because not informative. N.A. = not available