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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Oral Oncol. 2017 Jun 27;71:156–162. doi: 10.1016/j.oraloncology.2017.06.009

Figure 5. Papilloma detectable by white light reflectance with low RACPP signal.

Figure 5

A. Color image under white light and B. pseudo-color ratiometric fluorescence image showing a large lesion on the dorsal tongue (arrow) in a wild type mouse. C. Confocal image of a sagittal section of tissue across the lesion. There is some evidence of chronic inflammation in the superficial stroma indicated by high fluorescence signal. D. H&E image at the level of boxed region in C showing that the lesion in A and B features benign hyperkeratosis and hyperplasia with finger-like stromal expansion characteristic of papilloma.