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. 2017 Aug 29;17:585. doi: 10.1186/s12885-017-3579-8

Table 2.

Pre-diagnostic use of warfarin compared to anticoagulant non-users and warfarin usage in comparison with other anticoagulant drugs stratified by Defined Daily Doses (DDD), duration and intensity of usage

n of deaths Age-adjusted Multivariable-adjusted
Warfarin compared to non-users
 None 624 Ref Ref
 Any 65 1.11 (0.85-1.44) 1.15 (0.88-1.49)
Amount of warfarin use
 ≤200 DDD 24 0.98 (0.65-1.48) 0.97 (0.64-1.47)
 201-796 DDD 18 1.09 (0.68-1.74) 1.19 (0.74-1.91)
 >796 DDD 23 1.31 (0.86-1.99) 1.37 (0.90-2.09)
Duration of warfarin use
 ≤1 year 20 0.91 (0.53-1.56) 0.72 (0.42-1.24)
 2-4 years 22 0.96 (0.57-1.61) 0.87 (0.52-1.47)
 5 or more years 23 1.33 (0.80-2.23) 1.16 (0.69-1.94)
Intensity of warfarin use
 ≤114 DDD/year 21 0.95 (0.56-1.62) 0.79 (0.47-1.35)
 115-200 DDD/year 24 1.09 (0.65-1.81) 0.94 (0.57-1.57)
 >200 DDD/year 20 1.10 (0.64-1.89) 0.96 (0.56-1.65)

Age-adjusted and multivariable-adjusted hazard ratios (95% CI) related to all PCa deaths