Table 3.

Gestational nicotine exposure-modified gene expression in Wiskott–Aldrich syndrome protein family (WASP) and actin-related protein 2/3 complex (ARP2/3)

	Gene symbol	Gene name	Fold change (mean±S.D.)
			CPu	NAc	PFC	Amy
WASP	Nwasp	Wiskott–Aldrich syndrome-like (human)	0.47±0.05	0.06±0.02**	0.94±0.32	2.84±0.30*
	Wave2	WAS protein family, member 2	0.78±0.28	0.85±0.35	1.01±0.13	0.95±0.02
	Wave3	WAS protein family, member 3	0.81±0.32	0.86±0.24	1.36±0.11**	1.22±0.26
ARP2/3	Arpc1b	Actin related protein 2/3 complex, subunit 1B	0.69±0.06*	0.9±0.41	1.27±0.13*	1.25±0.09
	Arpc3	Actin related protein 2/3 complex, subunit 3	0.62±0.02***	0.82±0.02	1.06±0.03*	0.86±0.17
	Arpc4	Actin related protein 2/3 complex, subunit 4	0.65±0.18	0.62±0.05**	1.11±0.08	0.95±0.23
	Actr2	ARP2 actin-related protein 2 homolog (yeast)	0.34±0.24*	0.72±0.19	1.02±0.02	0.9±0.19
	Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.66±0.17	0.68±0.05	0.8±0.23	0.26±0.19

CPu, Caudate putamen; NAc, nucleus accumbens; PFC, prefrontal cortex; Amy, amygdala.

The effect of gestational nicotine exposure on mRNA expression of Wiskott–Aldrich syndrome protein family and actin-related protein 2/3 complex. Data are from PCR array.

^*p<0.05,

^**p<0.01,

^***p<0.001 significantly modified by gestational nicotine exposure compared with gestational saline-treated animals.