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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Antiviral Res. 2017 Jul 1;145:1–5. doi: 10.1016/j.antiviral.2017.06.022

Figure 1.

Figure 1

MacSynergy plots of the interaction of cidofovir and 6-azauridine in inhibiting vaccinia virus plaque formation in Vero 76 cells. The expected value (Y axis) for each drug combination is zero, assuming no synergy or antagonism. Values falling above or below the plane represent additive/synergistic or antagonistic interactions, respectively. The Volume of Synergy for this interaction is 275, which is interpreted as strong synergy. Results are from three independently performed plaque reduction assays.