Table 1.

Sites of Previously Reported CIC-rearranged Tumors.^a

Primary Site	Number of Cases	Age (years)	References
Trunk wall and head and neck soft tissue	31	Median 25 (range 6–73)	2–5, 7–10
Limbs	34	Median 32.5 (range 6–62)	5, 7–10
Internal trunk	6	Median 23.5 (range 19–40)	5, 7, 9
Primary bone	3	Median 44 (range 14–47)	5, 7, 10
Viscerab and adjacent structures	6	Median 25.5 (range 9–37)	2, 5, 7, 9, 12
Brainc	11	Adults are 64 and 24	9, 13, 14
		Median of 1.5 in EFT-CIC cases (range < 1–8)d

EFT-CIC, Ewing family of tumors with CIC alteration.

^aThis tally of cases excludes some reports. The overall median presenting age for tumors at peripheral sites from these reports is 29 years (range 6–73 years).

^bVisceral sites include lung, stomach, and kidney.

^cThe brain case reported in Yoshida et al.⁹ is also fully presented as a case report by Ito et al. A case report of CIC-rearranged undifferentiated small round cell sarcoma in the cerebrum. Diagn Cytopathol. 2016; 44: 828–832.

^dData obtained from supplemental data accessible from the online version of Sturm et at.¹⁴