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. Author manuscript; available in PMC: 2018 Mar 16.
Published in final edited form as: Math Med Biol. 2018 Mar 14;35(1):79–119. doi: 10.1093/imammb/dqw021

Fig. A1.

Fig. A1

Daclizumab does not inhibit proliferation of activated T cells, but prolongs their survival, while exerting little effect on IL-2 induced STAT5 phosphorylation. (A) Activated T cells were cultured with MA251 or Daclizumab (Dac) for 8 days. Absolute counts of cells were determined by flow cytometry. (B) CFSE-stained activated T cells were cultured for 7 days. Proliferation of activated T cells with high-affinity(MA251) or intermediate-affinity(Dac) IL-2R was determined by flow cytometry. (C) Phosphorylation of STAT5 by measuring mean fluorescent intensity (MFI) at 10 and 30 minutes after exogenous IL-2 is given.