Table 2.

Characteristics associated with tuberculosis infection status in child contacts of drug-susceptible tuberculosis and multidrug-resistant tuberculosis

	Total	Infected N (%)	OR (95%CI)	AOR (95% CI)
Child factors
Age < 2 years	203	64 (31.5%)	ref	ref
Age ≥ 2 years	335	144 (43%)	1.64 (1.13, 2.36)	1.61 (1.09, 2.37)
Female	259	96 (37.1%)	ref	ref
Male	278	112 (40.3%)	1.15 (0.81, 1.62)	1.02 (0.70, 1.47)
Mixed race / other ethnicity	390	161 (41.3%)	ref	ref
Black African ethnicity	148	47 (31.8%)	0.66 (0.44, 0.99)	0.54 (0.33, 0.88)
HIV-negative	518	202 (39%)	ref	ref
HIV-positive	9	3 (33.3%)	0.78 (0.19, 3.16)	0.66 (0.15, 2.94)
No BCG scar /no vaccination documented	45	16 (35.6%)	ref	ref
BCG scar/vaccination documented	487	191 (39.2%)	1.17 (0.62, 2.21)	1.62 (0.80, 3.29)
No prior tuberculosis treatment (disease)	509	189 (37.1%)	ref	ref
Prior tuberculosis treatment (disease)	29	19 (65.5%)	3.22 (1.47, 7.06)	2.36 (1.03, 5.39)
Weight for age (z-score) ≥ −2	482	186 (38.6%)	ref	ref
Weight for age (z-score) < −2	54	21 (38.9%)	1.01 (0.57, 1.80)	1.04 (0.56, 1.92)
Sleeps in different room to TB source case	348	132 (37.9%)	ref	ref
Sleeps in same room as TB source case	113	40 (35.4%)	0.90 (0.58, 1.40)	0.85 (0.53, 1.36)
Sleeps in same bed as TB source case	77	36 (46.8%)	1.44 (0.87, 2.36)	1.05 (0.60, 1.82)
Adult source case/household factors
DS-TB source case	312	107 (34.3%)	ref	ref
MDR-TB source case	226	101 (44.7%)	1.55 (1.09, 2.20)	2.05 (1.34, 3.12)
No household tobacco smoke exposure	144	50 (34.7%)	ref	ref
Household tobacco smoke exposure	394	158 (40.1%)	1.26 (0.85, 1.87)	1.22 (0.76, 1.94)
Socioeconomic index ≥ 5/11	419	165 (39.4%)	ref	ref
Socioeconomic index <5/11	119	43 (36.1%)	0.87 (0.57, 1.33)	0.79 (0.51, 1.25)

MDR-TB Mycobacterium tuberculosis resistant to rifampicin and isoniazid (defined by line probe assay)

DS-TB Mycobacterium tuberculosis susceptible to rifampicin and isoniazid (defined by line probe assay)