Table 3.

Characteristics associated with tuberculosis disease in child contacts of drug-susceptible tuberculosis and multidrug-resistant tuberculosis, among children with tuberculosis infection

	Total	Disease N (%)	OR (95% CI)	AOR (95% CI)
Child factors
Age < 2 years	64	20 (31.3%)	ref	ref
Age ≥ 2 years	144	22 (15.3%)	0.40 (0.20, 0.80)	0.32 (0.15, 0.71)
HIV negative	202	40 (19.8%)	ref	ref
HIV positive	3	2 (66.7%)	8.10 (0.72, 91.57)	23.0 (1.11, 477.86)
No BCG scar / no vaccination documented	16	3 (18.8%)	ref	ref
BCG scar / vaccination documented	191	39 (20.4%)	1.11 (0.30, 4.09)	1.14 (0.21, 6.20)
Weight for age (z-score) ≥ −2	186	34 (18.3%)	ref	ref
Weight for age (z-score) < −2	21	7 (33.3%)	2.24 (0.84, 5.96)	2.17 (0.72, 6.55)
Adult source case factors
DS-TB	107	27 (25.2%)	ref	ref
MDR-TB	101	15 (14.9%)	0.52 (0.26, 1.04)	0.43 (0.19, 0.97)
Smear-negative source case	43	4 (9.3%)	ref	ref
Smear-positive source case	155	35 (22.6%)	2.84 (0.95, 8.51)	4.24 (1.31, 13.78)

MDR-TB Mycobacterium tuberculosis resistant to rifampicin and isoniazid (defined by line probe assay)

DS-TB Mycobacterium tuberculosis susceptible to rifampicin and isoniazid (defined by line probe assay)