Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Oct 1;27(10):684–712. doi: 10.1089/ars.2017.7083

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Miriam M. Cortese-Krott, et al., 2017; Published by Mary Ann Liebert, Inc.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

FIG. 3. — Cysteine modifications induced by interaction with ROS, RNS, and RSS. The reactive species interactome consists of the interaction of reactive species (ROS, RNS, and RSS) with one another and with cysteine thiols as redox switches (reactions with other functional groups omitted here for the sake of simplicity). The outcome of these interactions depends on the chemical characteristics of the species inducing the modification (e.g., O₂^•−, H₂O_2, NO, ONOO⁻) and their fluxes and the environmental conditions (e.g., pO₂, pH), as well as on the reactivity and localization of the targeted cysteines. The lines indicate the outcome of protein cysteine modifications induced by RNS (blue), ROS (red), or RSS (orange).