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. 2017 Aug 29;19:101. doi: 10.1186/s13058-017-0895-5

Table 2.

Type of toxicity among patients with treatment-related grade 3–5 toxicities (N = 70 patients)

Toxicity type Grade 3–4 toxicities
Hematologic
 Anemia 13 38%
 White blood cell count decreased 10 29%
 Neutrophil count decreased 8 24%
 Bleeding 3 9%
Non-hematologic
 Metabolic abnormalities 14 12%
 Nausea/vomiting 13 11%
 Neuropathy 12 10%
 Mucositis 9 8%
 Infection 9 8%
 Fatigue 9 8%
 Diarrhea 6 5%
 Arrhythmia 5 4%
 Left ventricular systolic dysfunction 5 4%
 Pain 5 4%
 Dehydration 4 3%
 Allergy 3 2.5%
 Hypotension 3 2.5%
 Syncope 3 2.5%
 Kidney dysfunction 3 2.5%
 Dizziness 2 1.7%
 Othersa 1 0.8%

Results are presented as number and percentage of patients

aOthers: depression, falls, dysphagia, abnormal liver enzyme, bowel perforation, constipation, sore throat, aspiration, embolism, hand-foot syndrome