Table 7.
Multivariate association between biomarkers and RDI < 85%
| Biomarkers/Clinical factors | Odds ratio (95%CI) | P value |
|---|---|---|
| IL-6 or D-dimer combinationa | ||
| 1 or 2 vs. 0 | 2.54 (1.03–6.23) | 0.04 |
| Age | 1.06 (1.02–1.10) | <0.01 |
| Physical function measured by MOS-ADLb | 0.98 (0.96–1.00) | 0.04 |
| Breast cancer stage | ||
| Stage II vs. I | 0.66 (0.22–1.98) | 0.46 |
| Stage III vs. I | 0.23 (0.05–0.97) | 0.04 |
| Anthracycline-containing regimen | ||
a IL-6 or D-dimer combination: 0 = both markers in lower three quartiles; 1 = 1or 2 of the markers in the 4th quartile
bMOS-ADL: Activities of Daily Living (subscale of MOS physical health)