Figure 1.
Highly schematized cartoon of TFs assembled onto a tRNA gene (3) that also reflects the relative evolutionary conservation of individual TFIIIB and TFIIIC subunits, as described in the text. For most of the subunits the nomenclature follows that for S.cerevisiae (4). The positions of the A box and B box promoter elements are indicated. The arrow indicates the direction and site of initiation of transcription. T indicates the site of transcription termination. The minimal numbers of T sites required for efficient termination by S.cerevisiae (6, S. c.), S.pombe (5, S. p.) and human (4, H. s.) pols III are indicated schematically (8).