Table 1. Summary of therapeutic response to pembrolizumab (anti-PD-1) treatment.

Radiographic responses, progression-free survival (PFS) and overall survival (OS) estimates were measured using the Response Evaluation Criteria In Solid Tumors (RECIST v1.1) guidelines. Patients were considered not evaluable if they did not undergo a 12-week scan due to clinical progression. The rate of disease control was defined as the percentage of patients who had a complete response, partial response, or stable disease for 12 weeks or more. NR, not reached.

Type of response	Patients (n = 86)
Complete response	18 (21%)
Partial response	28 (33%)
Stable disease	20 (23%)
Progressive disease	12 (14%)
Not evaluable	8 (9%)
Objective response rate 95% CI	53% 42% to 64%
Disease control rate 95% CI	77% 66% to 85%
Median progression-free survival time 95% CI	NR 14.8 months to NR
2-year progression-free survival rate 95% CI	53% 42% to 68%
Median overall survival time 95% CI	NR NR to NR
2-year overall survival rate 95% CI	64% 53% to 78%