. 2017 Aug 29;14:171. doi: 10.1186/s12974-017-0929-z

Table 9.

Summary of differences in CSF parameters between various MS subgroups as observed in the present study

Parameter	Diagnostic groups	Results	P values
CSF-restricted OCB, all LPs	Pattern I	15/17 (88.2)	P < 0.00004
	Patterns II + III	10/37 (27)
	Reiber et al. [19]	262/267 (98)	P < 0.000001
	Patterns II + III	10/37 (27)
	Pattern I	15/17 (88.2)	P < 0.0001
	Pattern II	9/25 (36)
	Pattern III	1/12 (8.3)
CSF-restricted OCB, patients	Pattern I	8/10 (80)	P < 0.03
	Patterns II + III	7/22 (31.8)
	Reiber et al. [19]	262/267 (98)	P < 0.000001
	Patterns II + III	7/22 (31.8)
CSF-restricted OCB, patients, w/o transient OCBs	Pattern I	8/10 (80)	P < 0.006
	Patterns II + III	5/22 (22.7)
	Reiber et al. [19]	262/267 (98)	P < 0.00001
	Patterns II + III	5/22 (22.7)
MRZ reaction (≥2 AIs >1.5), all LPs	Jarius et al. [23]	397/546 (69)	P < 0.000001
MRZ reaction (≥2 AIs >1.5), all LPs	Patterns II + III	0/12 (0)
M and/or R and/or Z >1.5, all LPs	Reiber et al. [19]	158/177 (89)	P < 0.000001
M and/or R and/or Z >1.5, all LPs	Patterns II + III	0/12 (0)
QIgG > Q_lim(lgG), all LPs	Pattern I	7/17 (41.2)	P < 0.03
QIgG > Q_lim(lgG), all LPs	Patterns II + III	5/41 (12.2)
QAlb > Q_lim(Alb), all LPs	Pattern I	4/17 (23.5)	P < 0.002
	Patterns II + III	30/43 (69.8)
	Pattern I	4/17 (23.5)	P = 0.002
	Pattern II	16/26 (61.5)
	Pattern III	14/17 (82.4)
QAlb, all LPs	Pattern I	4.81 (3.01–10.8; 17)	P < 0.005
QAlb, all LPs	Patterns II + III	8.39 (2.1–33.9; 42)
Albumin CSF, all LPs	Pattern I	204 (95–517; 17)	P < 0.009
Albumin CSF, all LPs	Patterns II + III	331 (81.2–726; 41)
Total CSF protein elevated, all LPs	Pattern I	3/15 (20)	P < 0.003
Total CSF protein elevated, all LPs	Patterns II + III	29/43 (67.4)
Total CSF protein, all LPs	Pattern I	375 (187–750; 15)	P < 0.007
Total CSF protein, all LPs	Patterns II + III	550 (168–1930; 43)
Albuminocytological dissociation, all LPs	Pattern I	1/8 (12.5)	P < 0.04
Albuminocytological dissociation, all LPs	Patterns II + III	13/21 (61.9)