Fig. 1.
Assay breakdown of toxicity screening in iPSC-derived ECs and HUVECs. In this study, we present a multidimensional comparison of high-throughput in vitro assays for assessing the alterations in vascularization (angiogenesis assays in both Geltrex™ and SP-105 hydrogel) and cell viability (Hoechst Nuclei Content, Viable Cell Staining with Calcein AM and ATP content with CellTiter-Glo®) caused by chemicals. EC, endothelial cell; HUVEC, human umbilical vein endothelial cell; iPSC, induced pluripotent stem cell.
