Table 2.

Multivariate Analyses of Covariate Associations with IGF-1 Serum Levels at Baseline and Change in Insulin-Like Growth Factor -1 from Baseline to 96 Weeks

Covariate	Coefficient	SE	p
Baseline IGF-1 level associations with baseline covariatesa
Age, years	−1.61	0.30	<.0001
Race (white, reference)	0.00
Black	−16.77	7.42	.02
Other race	−28.14	9.03	.002
Baseline WHR (per 0.1 change)	−11.68	4.17	.005
CD4 count (>200 cells/μl)	13.47	5.88	.02
Albumin (g/dl)	24.60	5.51	<.0001
Baseline to week 96 change IGF-1 level associations with baseline and change covariatesb
Female sex	13.33	5.16	.01
Change in WHR (per 0.1 change)	−10.56	3.66	.004
HIV-1 RNA level (>log5)	−11.39	4.86	.02
Albumin (g/dl)	−10.80	4.50	.02

^aAlso included sex, HIV-1 RNA, BMI, treatment group.

^bAlso included age, race, BMI week 96, CD4+ count week 96, baseline to week 96 change in CD4+ count, baseline to week 96 change in BMI, WHR week 96, and treatment group.

IGF-1, insulin-like growth factor-1.