Table 3.
Characteristics of interval cancers and screen-detected colorectal cancer
| Total | Interval cancersa | Screen-detected | p-value | |
|---|---|---|---|---|
| First round | Second round | |||
| 136 (83.3%; 1st round/16.2%; 2nd round) | 889 | 143 | - | |
| Sex | ||||
| Men; n (%) | 89 (65.4) | 594 (66.8) | 99 (69.2) | 0.79 |
| Women; n (%) | 47 (34.6) | 295 (33.2) | 44 (30.8) | |
| Age (years) | ||||
| 50–54; n (%) | 26 (19.1) | 137 (15.4) | 19 (13.3) | 0.06 |
| 55–59; n (%) | 32 (23.5) | 195 (21.9) | 42 (29.4) | |
| 60–64; n (%) | 45 (33.1) | 260 (29.2) | 43 (30.1) | |
| 65–69; n (%) | 33 (24.3) | 297 (33.4) | 39 (27.3) | |
| μg Hb/g faeces; median (IQR) | 2.9 (0.4–11.6)b | 201.8 (74.4–589.8)c | 638.3 (56.8–617.2)c | - |
| Location (proximal side/distal side/rectum)c; % | 34.3 / 33.6 / 32.1 | 18.1 / 67.0 / 14.9 | 21.6 / 66.3 / 12.1 | <0.001 |
| Stage (I-II/III-IV); % | 44.8 / 55.2 | 66.7 / 28.4 | 65.7 / 24.6 | <0.001 |
| Size (cm); median (IQR) | 8 (6.0–12.0) | 2.5 (1.5–4.0) | 2.5 (1.5–3.5) | <0.001 |
| Time to diagnosis | ||||
| Within 1 year; n (%) | 64 (47.1) | - | ||
| 1–2 years; n (%) | 72 (52.9) | |||
aInterval cancers after a negative test result in the previous round
bMedian μg Hb/g faeces at time of negative screening test result. **Median μ Hb/g faeces at time of positive screening test result
cProximal side includes regions from cecum up to and including the transverse colon; distal side includes splenic flexure, descending colon and sigmoid colon