Table 1.
Clinical and demographic features of patients with different types of WSI
| Variable | CWI (n = 92) |
IWI (n = 112) |
Mixed-type (n = 136) |
P |
|---|---|---|---|---|
| Male, n (%) | 54 (58.7) | 73 (65.2) | 93 (68.4) | 0.321 |
| Age, years | 65.46 ± 10.42 | 66.12 ± 10.89 | 64.54 ± 11.26 | 0.429 |
| Risk factors, n (%) | ||||
| Hypertension | 60 (65.2) | 79 (70.5) | 93 (68.4) | 0.718 |
| Diabetes mellitus | 27 (29.3) | 36 (32.1) | 43 (31.6) | 0.903 |
| Hyperlipidemia | 48 (52.2) | 60 (53.6) | 63 (46.3) | 0.480 |
| PSCE | 22 (23.9) | 14 (12.5) | 20 (14.7) | 0.071 |
| Smoking | 53 (57.6) | 72 (64.3) | 82 (60.3) | 0.613 |
| Stroke / TIA | 28 (30.4) | 38 (33.9) | 52 (38.2) | 0.468 |
| CAD | 21 (22.8) | 15 (13.4) | 16 (11.8) | 0.059 |
| SBP, mmHg | 147.43 ± 25.13 | 154.45 ± 23.07 | 152.87 ± 23.78 | 0.791 |
| DBP, mmHg | 85.32 ± 11.45 | 87.23 ± 12.87 | 86.24 ± 11.89 | 0.613 |
| Laboratory data | ||||
| TC, mmol/L | 4.32 ± 1.12 | 4.69 ± 0.93 | 4.54 ± 1.18 | 0.512 |
| TG, mmol/L | 1.23 (0.92, 1.89) | 1.49 (0.98, 2.16) | 1.37 (1.02, 2.09) | 0.897 |
| HDL, mmol/L | 1.19 ± 0.31 | 1.36 ± 0.27 | 1.37 ± 0.39 | 0.318 |
| LDL, mmol/L | 2.52 ± 0.71 | 2.69 ± 0.67 | 2.62 ± 0.62 | 0.634 |
| HbA1c, % | 6.40 (5.60, 7.90) | 6.50 (5.80, 8.10) | 6.40 (5.70, 7.80) | 0.692 |
| Albumin, g/L | 37.62 ± 4.87 | 37.66 ± 4.14 | 37.21 ± 4.54 | 0.941 |
| Fibrinogen, mg/dl | 334.76 ± 65.87 | 326.86 ± 71.23 | 313.23 ± 70.65 | 0.327 |
| HCY, mmol/L | 17.00 (14.00, 20.00) | 19.00 (15.00, 24.00) | 18.00 (15.00, 23.00) | 0.093 |
| Hs-CRP, mg/L | 2.45 (1.17, 7.83) (1.06,8.65) |
2.54 (1.21, 6.87) | 2.64 (1.15, 5.45) | 0.432 |
| Cr, μmol/L | 84.76 (70.87, 105.92) | 85.16 (75.32, 97.98) | 84.94 (73.66, 99.72) | 0.675 |
| Uric acid, μmol/L | 321.87 ± 91.76 | 319.76 ± 98.65 | 312.55 ± 97.60 | 0.821 |
Data are presented as mean ± standard deviation, median (interquartile range) or counts (%)
WSI Watershed infarction, CWI Cortical watershed infarction, IWI Internal watershed infarction, N Number of persons, PSCE Potential sources of cardioembolism, TIA Transient ischemic attack, CAD Coronary artery disease, SBP Systolic blood pressure, DBP Diastolic blood pressure, TC Total cholesterol, TG Triglyceride, HDL High density lipoprotein, LDL Low density lipoprotein, HbA1c Glycosylated hemoglobin, HCY Homocysteine, Hs-CRP High-sensitivity C-reactive protein, Cr Serum creatinine