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. 2017 Aug 29;17:426. doi: 10.1186/s12906-017-1931-9

Fig. 4.

Fig. 4

a Linear correlation curve of the P. gingivalis’ DNA copy number and cytokines in periodontal tissue (IL-1β and TNF-α). The integrated optical densities of IL-1β and TNF-α were calculated on the basis of immunohistochemical staining. The levels of IL-1β and TNF-α in rat periodontal tissue showed a significant positive linear correlation with DNA copy number of P. gingivalis (P < 0.05). b Linear correlation curve of the total bacteria DNA copy number and cytokines in periodontal tissue (IL-1β and TNF-α). The integrated optical densities of IL-1β and TNF-α were calculated on the basis of immunohistochemical staining. There was not a significant positive linear correlation between IL-1β or TNF-α expression levels in rat periodontal tissue and DNA copy number of total bacteria (P > 0.05)