Table 2.

Outcomes in the 322-patient prospective cohort and correlation with GEP class, SLN status, and ulceration

	Recurrence (n* = 25)	Distant metastasis (n = 12)	Death (n = 11)
Class 1 (n = 248)	5 (2%)	2 (1%)	3 (1%)
Class 2 (n = 74)	20 (27%)	10 (14%)	8 (11%)
p value**	<0.0001	<0.0001	0.0001
SLN− (n = 286)	15 (5%)	6 (2%)	10 (3%)
SLN+ (n = 36)	10 (28%)	6 (17%)	1 (3%)
p value	<0.0001	<0.001	1
Ulceration absent (n = 264)	10 (4%)	3 (1%)	6 (2%)
Ulceration present (n = 58)	15 (26%)	9 (16%)	5 (9%)
p value	<0.0001	<0.0001	0.04

*n = number of samples

**p values reflect differences between high and low-risk groups for each prognostic factor (χ ² test)