Table 1.

Sequencing results of cross-linked and native ChIP-seq on muscle samples. Two biological replicates were sequenced for each chromatin immunoprecipitation method (X-ChIP and N-ChIP). Reads were mapped against the chicken genome Galgal5, and peaks were detected using epic. When indicated (40 M), analyses were performed on 40 million of unique reads per sample that were randomly selected for both H3K27me3 and input fractions. Genome coverage is expressed in Megabases

Method	X-ChIP				N-ChIP
Sample	X_R1		X_R2		N_R1		N_R2
Fraction	Input	H3K27me3	Input	H3K27me3	Input	H3K27me3	Input	H3K27me3
Total number of reads (millions)	57.37	119.58	60.29	123.37	57.98	92.93	58.94	128.56
Total number of uniquely mapped reads (millions)	51.16	106.36	52.55	104.29	45.17	69.58	46.51	92
Total peak number	2127		2519		16,446		13,949
Total genome coverage (Mb)	7.87		9.75		73.52		71.14
40 M peak number	1264		1484		14,128		11,900
40 M genome coverage (Mb)	4.76		5.21		60.51		51.21