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. 2017 Aug 29;17:78. doi: 10.1186/s12935-017-0447-1

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — miR-222influence on migration and invasion of HCT8 cells. a, b Transwell migration (n = 4) and invasion (n = 4) assays showed that HCT8 cells transfected with the miR-222 mimics (800 nM) had higher invasive and migratory potentials than the control (mimics control). a A microscopic image of crystal violet staining. b The statistical results. c, d Transwell migration (n = 4) and invasion (n = 4) assays showed that HCT8 cells transfected with the miR-222 inhibitor (800 nM) had lower invasive and migratory potentials than the control (inhibitor control). c A microscopic image of crystal violet staining. d The statistical results. Data represent the mean ± SD of four independent experiments. *P < 0.05