Table 5.
The top ten most commonly prescribed formulas for patients with dysfunctional uterine bleeding
| Pin-yin name | English name | Constitutions | Indication for TCM syndrome | Frequency of prescription, times (%) | Average daily dose (g) | |||
|---|---|---|---|---|---|---|---|---|
| Pin-yin name | Chinese material medica name | Botanical name | DUB related | DUB unrelated | ||||
| Jia-Wei-Xiao-Yao-San | Bupleurum and Peony Formula | Dang-Gui | Radix Angelicae Sinensis | Angelica sinensis (Oliv.) Diels | Irregular menstruation because of spleen qi deficiency and liver blood deficiency with heat, liver qi stagnation | Irritability, abdominal pain, depression | 7654 (0.14) | 7.3 |
| Fu-Ling | Poria, | Poria cocos (Schw.) Wolf | ||||||
| Zhi-Zi | Fructus Gardeniae | Gardenia jasminoides J.Ellis | ||||||
| Bo-He | Herba Menthae Haplocalycis | Mentha haplocalyx Briq.Field | ||||||
| Bai-Shao | Radix Paeoniae Alba | Paeonia lactiflora Pall | ||||||
| Chai-Hu | Radix Bupleuri | Bupleurum chinense DC. | ||||||
| Gan-Cao | Radix Glycyrrhizae | Glycyrrhiza uralensis Fisch | ||||||
| Bai-Zhu | Rhizoma Atractylodis Macrocephalae | Atractylis macrocephala Koidz | ||||||
| Mu-Dan-Pi | Cortex Moutan Radicis | Paeonia suffruticosa Andr. | ||||||
| Wei-Jiang | Rhizoma Zingiberis officinales | Zingiber officinale Rosc. | ||||||
| Dang-Gui-Shao-Yao-San | Dang Gui and Peony Powder | Dang-Gui | Radix Angelicae Sinensis | Angelica sinensis (Oliv.) Diels | Liver blood deficiency | Abdominal pain, dizziness, edema with inhibited urination | 3147 (0.06) | 6.6 |
| Fu-Ling | Poria | Poria cocos (Schw.) Wolf | ||||||
| Bai-Shao | Radix Paeoniae Alba | Paeonia lactiflora Pall. | ||||||
| Bai-Zhu | Rhizoma Atractylodis Macrocephalae | Atractylodes macrocephala Koidz | ||||||
| Chuan-Xiong | Rhizoma Chuanxiong | Ligusticum chuanxiong Hort. | ||||||
| Ze-Xie | Rhizoma Alismatis | Alisma plantago-aquatica L. | ||||||
| Gui-Zhi- Fu-Ling-Wan | Cinnamon and Poria Pills | Gui-Zhi | Ramulus Cinnamomi Cassiae | Cinnamomum cassia Blume | Blood stasis in pelvic cavity | Lower abdominal pain | 2841 (0.05) | 6.6 |
| Fu-Ling | Poria | Poria cocos (Schw.) Wolf | ||||||
| Mu-Dan-Pi | Cortex Moutan Radicis | Paeonia suffruticosa Andr. | ||||||
| Chi-Shao | Radix Paeoniae Lactiforae | Paeonia lactiflora Pall. | ||||||
| Tao-Ren | Semen Persicae | Prunus persica (L.) Batsch. | ||||||
| Wen-Jing-Tang | Flow warming decoction | Wu-Zhu-Yu | Fructus Evodiae Rutaecarpae | Evodia rutaecarpa (Juss.) Benth. | Blood stasis | 2345 (0.04) | 6.7 | |
| Gui-Zhi | Ramulus Cinnamomi Cassiae | Cinnamomum cassia Blume | ||||||
| Dang-Gui | Raidx Angelicae Sinensis | Angelica sinensis (Oliv.) Diels | ||||||
| Chuan-Xiong | Radix Chuanxiong | Ligusticum chuanxiong Hort. | ||||||
| Bai-Shao | Radix Paeoniae Alba | Paeonia lactiflora Pall. | ||||||
| E-Jiao | Colla Corii Asini | Equus asinus L. | ||||||
| Mai-Men-Dong | Tuber Ophiopogonis Japonici | Ophiopogon japonicas (Thunb.) Ker_Gawl | ||||||
| Mu-Dan-Pi | Cortex Moutan Radicis | Paeonia suffruticosa Andr. | ||||||
| Ren-Shen | Radix Ginseng | Panax ginseng C. A. Mey | ||||||
| Gan-Cao | Radix Glycyrrhizae | Glycyrrhiza uralensis Fisch | ||||||
| Sheng-Jiang | Rhizoma Zingiberis officinales | Zingiber officinale Rosc. | ||||||
| Ban-Xia | Rhizoma Pinelliae Ternatae | Pinellia ternate (Thunb.) Breit | ||||||
| Xiong-Guei-Jiao-Ai-Tang | Decoction of Donkey-Skin Glue and Artemisia | Chuan-Xiong | Rhizoma Chuanxiong | Ligusticum chuanxiong Hort. | Blood deficiency | Prevents miscarriage | 3147 (0.06) | 6.4 |
| Dang-Gui | Raidx Angelicae Sinensis | Angelica sinensis (Oliv.) Diels | ||||||
| E-Jiao | Colla Corii Asini | Equus asinus L. | ||||||
| Gan-Cao | Radix Glycyrrhizae | Glycyrrhiza uralensis Fisch | ||||||
| Shu-Di-Huang | Radix Rehmanniae | Rehmannia glutinosa Libosch | ||||||
| Bai-Shao | Radix Paeoniae Alba | Paeonia lactiflora Pall | ||||||
| Ai-Ye | Folium Artemnisiae Argyi | Artemisia argyi Levl. et Vant. | ||||||
| Gui-Pi-Tang | Restore the Spleen Decoction | Ren-Shen | Radix Ginseng | Panax ginseng C. A. Mey | Blood deficiency, vaginal spotting because of qi deficiency | Diarrhea because of qi deficiency in spleen | 1812 (0.03) | 6.7 |
| Long-Yan-Rou | Arillus Euphoriae Longanae | Dimocarpus longans Lour. | ||||||
| Huang-Qi | Radix Astragali | Astragalus henryi Oliv. | ||||||
| Gan-Cao | Radix Glycyrrhizae | Glycyrrhiza uralensis Fisch | ||||||
| Bai-Zhu | Rhizoma Atractylodis Macrocephalae | Atractylis macrocephala Koidz | ||||||
| Fu-Ling | Poria | Poria cocos (Schw.) Wolf | ||||||
| Mu-Xiang | Radix Aucklandiae | Aucklandia lappa DC. | ||||||
| Dang-Gui | Raidx Angelicae Sinensis | Angelica sinensis (Oliv.) Diels | ||||||
| Suan-Zao-Ran | Semen Zizyphi Spinosae | Ziziphus jujube var. Spinosa (Bunge) Hu ex H. F. Chow | ||||||
| Yuan-Zhi | Radix Polygalae Tenuifoliae | Polygala tenuifolia Willd. | ||||||
| Sheng-Jiang | Radix Zingiberis officinalis | Zingiber officinale Rosc. | ||||||
| Da-Zao | Fructus Zizyphi Jujube | |||||||
| Ziziphus jujuba Mill. | ||||||||
| Si-Wu-Tang | Four Substances Decoction | Shu-Di-Huang | Radix Rehmanniae | Rehmannia glutinosa Libosch | Blood deficiency | 1554 (0.03) | 6.9 | |
| Bai-Shao | Radix Paeoniae Alba | Paeonia lactiflora Pall | ||||||
| Dang-Gui | Radix Angelicae Sinensis | Angelica sinensis (Oliv.) Diels | ||||||
| Chuan-Xiong | Rhizoma Chuanxiong | Ligusticum chuanxiong Hort. | ||||||
| Bu-Zhong-Yi-Qi-Tang | Tonify the Middle and Augment the Qi Decoction | Huang-Qi | Radix Astragali | Astragalus henryi Oliv. | Vaginal spotting because of qi deficiency | Weakness because of qi deficiency | 1317 (0.02) | 6.7 |
| Ran-Shen | Radix Ginseng | Panax ginseng C. A. Mey | ||||||
| Bai-Zhu | Rhizoma Atractylodis Macrocephalae | Atractylis macrocephala Koidz | ||||||
| Gan-Cao | Radix Glycyrrhizae | Glycyrrhiza uralensis Fisch | ||||||
| Dang-Gui | Radix Angelicae Sinensis | Angelica sinensis (Oliv.) Diels | ||||||
| Chen-Pi | Pericarpium Citri Reticulatae | Citrus reticulate Blanco | ||||||
| Sheng-Ma | Radix Cimicifugae | Cimicifuga foetida, L. var., intermedia, Regel | ||||||
| Chai-Hu | Radix Bupleuri | Bupleurum chinense DC. | ||||||
| Liu-Wei-Di-Huang-Wan | Six Ingredient Pill with Rehmannia | Shu-Di-Huang | Radix Rehmanniae | Rehmannia glutinosa Libosch | Deficiency in liver and kidney | 1286 (0.02) | 7.2 | |
| Shan-Zhu-Yu | Fructus corni officinalis | Cornus officinalis Sieb. et Zucc. | ||||||
| Shan-Yao | Radix Dioscoreae Oppositae | Dioscorea opposite Thunb. | ||||||
| Fu-Ling | Poria | Poria cocos (Schw.) Wolf | ||||||
| Mu-Dan-Pi | Cortex Moutan Radicix | Paeonia suffruticosa Andr. | ||||||
| Ze-Xie | Rhizoma Alismatis | Alisma orientale (Sam.)Juzep. | ||||||
| Shao-Fu-Zhu-Yu-Tang | Drive Out Stasis from the Lower Abdomen Decoction | Xiao-Hui-Xiang | Fructus Foenichli Vulgaris | Foeniculum vulgare Mill. | Blood stasis and qi stagnation | 1030 (0.02) | 7.8 | |
| Pao-Jiang | Rhizoma Zingiberis officinales | Zingiber officinale Rosc. | ||||||
| Yan-Hu-Suo | Rhizoma Corydalis | Corydalis yanhusuo W. T. Wang | ||||||
| Dang-Gui | Radis Angelicae Sinensis | Angelica sinensis (Oliv.) Diels | ||||||
| Chuan-Xiong | Rhizoma Chuanxiong | Ligusticum chuanxiong Hort. | ||||||
| Mo-Yao | Myrrh | Commiphora molmol, Engi. | ||||||
| Rou-Gui | Ramulus Cinnamomi Cassiae | Cinnamomum cassia Blume | ||||||
| Chi-Shao | Radix Paeoniae Lactiflorae | Paeonia lactiflora Pall. | ||||||
| Pu-Huang | Pollen Typhae | Typha angustifolia L. | ||||||
| Wu-Ling-Zhi | excrementum Trogopteri Xanthipes | Trogopterus xanthipes Milne-Edwards | ||||||
Abbreviation: TCM traditional Chinese medicine, DUB dysfunctional uterine bleeding
Frequency indicates the used times of the specific herbal formula, and % indicates the used times of the specific herbal formula over the used times of all herbal formulas for DUB patients