Table 2.

Mean number of sequences per sample constituting the 15 taxa^a found in significantly different amounts in induced and spontaneous sputum from COPD patients with and without respect to disease state

	All samples			Exacerbation			Stable state
Taxonomyb	Induced	Spontaneous	pc	Induced	Spontaneous	pc	Induced	Spontaneous	pc
f_Prevotellaceae;g_Prevotella	2499.2	1760.3	<0.001	2633.1	1817.1	<0.001	2349.5	1763.0	<0.001
f_Pasteurellaceae;g_Haemophilus	1471.9	2440.3	<0.001	1308.2	2356.6	<0.001	1957.7	2859.8	<0.001
f_Moraxellaceae;g_Moraxella	259.2	542.3	<0.001	234.4	456.5	<0.001	353.9	798.0	0.001
f_Veillonellaceae;g_Veillonella	1488.3	1170.8	<0.001	1618.8	1173.1	<0.001
f_Veillonellaceae;g_Megasphaera	179.9	100.0	<0.001	201.9	111.5	<0.001	134.8	79.4	0.01
f_Corynebacteriaceae;g_Corynebacterium	44.9	12.0	<0.001	60.3	14.9	<0.001
f_Oxalobacteraceae;g_Ralstonia				423.3	604.7	<0.001	331.8	213.3	<0.001
f_Comamonadaceae;g_Curvibacter				518.7	713.0	<0.001	430.7	269.5	<0.001
f_Leptotrichiaceae;g_Leptotrichia				171.8	95.2	<0.001
f_Neisseriaceae;g_Neisseria							344.5	149.8	<0.001
f_Gemellaceae;g_Gemella							84.9	16.5	<0.001
f_Gemellaceae;g_							452.7	273.6	<0.001
f_Neisseriaceae;g_							79.5	17.5	<0.001
f_Leptotrichiaceae;g_Leptotrichia							123.6	217.6	<0.001
f_Actinomycetaceae;g_Actinomyces							350.1	256.0	0.001

^aRarefied OTU-tables: Sequences/Sample = 18,250 for All samples and Exacerbations, for Stable state: 19,743

^bGreenGenes Level 6: f_ = Name of family level g_ = Name of genus level. One hundred six different taxa in total

^clog-likelihood ratio test, Bonferroni corrected due to multiple comparisons