TABLE 2.

Ethnic-Specific Associations Between a Positive FH and the Presence and Burden of CAC (>0 and >300): The MASALA and MESA Studies Compared

	Odds Ratios for the Presence of Calcification by Race or Ethnicity With a Positive FH (95% Confidence Interval)
	MASALA South Asian	MESA				p Value*	p Value†
		Non-Hispanic White	African American	Hispanic	Chinese American
CAC >0 vs. 0
Unadjusted	1.14 (0.87–1.51)	1.58 (1.34–1.85)	1.50 (1.24–1.82)	1.66 (1.34–2.06)	1.24 (0.86–1.78)	0.21	0.94
Model 1‡	1.02 (0.71–1.45)	1.62 (1.34–1.97)	1.59 (1.28–1.97)	1.59 (1.23–2.05)	1.33 (0.89–1.98)	0.25	0.64
CAC >300 vs. ≤300
Unadjusted	2.06 (1.28–3.31)	1.66 (1.33–2.06)	1.38 (1.01–1.89)	2.43 (1.69–3.49)	1.47 (0.82–2.66)	0.18	0.35
Model 1‡	2.81 (1.60–4.93)	1.82 (1.42–2.33)	1.45 (1.03–2.05)	2.47 (1.65–3.69)	1.63 (0.86–3.10)	0.25	0.52

Values are odds ratios, 95% confidence intervals, and p values.

^*p value for interaction by ethnicity.

^†p value for interaction by age.

^‡Adjusted for age, sex, tobacco use, diabetes mellitus, systolic blood pressure, total cholesterol, high-density lipoprotein cholesterol, use of lipid-lowering medications, and use of medication for hypertension.

Abbreviations as in Table 1.