Skip to main content
. Author manuscript; available in PMC: 2018 May 2.
Published in final edited form as: Environ Sci Technol. 2017 Apr 11;51(9):5193–5204. doi: 10.1021/acs.est.6b05811

Table 4. Adjusted Associations from Multivariable Linear Regression Models for Predictors of PFAS Concentrations in Project Viva Midchildhood (age 6–10 years) Plasma Samples (n = 545).

% difference in PFAS concentration (95% CI)

PFOA PFOS PFHxS PFNA PFDeA Me-PFOSA-AcOH
Child Characteristics
Child's Age at Blood Draw (years) 2.5 (−4.4, 9.9) 8.6 (−0.9, 18.9) 15.3 (1.6, 30.9) −0.4 (−9.9, 10.1) −2.1 (−11.0, 7.6) 5.8 (−10.0, 24.6)
Year of Blood Draw
 2007 ref ref ref ref ref ref
 2008 5.7 (−7.9, 21.3) −4.1 (−19.9, 14.7) 10.4 (−14.0, 41.7) 40.5 (15.4, 71.1) 12.8 (−6.5, 36.0) 0.1 (−27.4, 37.9)
 2009 −17.1 (−27.8, −4.8) −28.8 (−40.6, −14.7) −23.8 (−40.8, −2.1) 34.5 (10.3, 64.1) −1.8 (−18.6, 18.6) −35.1 (−53.0, −10.4)
 2010 −31.0 (−42.1, −17.8) −38.5 (−51.1, −22.6) −43.9 (−59.2, −22.8) 29.1 (0.4, 66.0) −5.3 (−25.4, 20.3) −46.3 (−64.3, −19.1)
Sex
 male ref ref ref ref ref ref
 female 2.7 (−5.4, 11.5) −2.6 (−12.4, 8.5) −12.5 (−24.6, 1.6) 5.4 (−6.3, 18.5) 4.8 (−6.2, 17.2) −0.8 (−18.1, 20.1)
Breastfeeding Duration
 <3 months ref ref ref ref ref ref
 3–<6 months −4.4 (−17.1, 10.2) −5.2 (−21.3, 14.1) 0.4 (−22.5, 30.0) −6.8 (−24, 14.2) −8.1 (−24.3, 11.6) −4.9 (−31.7, 32.6)
 ≥6 months 2.6 (−6.7, 12.9) 8.4 (−4.3, 22.7) 10.9 (6.6, 31.8) −12.1 (−23.3, 0.8) −12.6 (−23.2, −0.5) 3.9 (−16.7, 29.6)
BMI in Midchildhood (Percentile)
 underweight/normal (<85th) ref ref ref ref ref ref
 overweight (85−<95th) −10.1 (−20.3, 1.5) −9.7 (−22.9, 5.7) −16.9 (−33.3, 3.5) −0.9 (−16.7, 17.9) −2.8 (−17.6, 14.6) −6.7 (−29.6, 23.7)
 obese (≥95fh) −12.1 (−22.4, −0.5) −7.2 (−21.1, 9.1) −8.0 (−26.6, 15.2) 3.2 (−13.6, 23.3) −15.6 (−28.7, −0.1) −1.2 (−26.0, 31.9)
Fast Food Consumption
 <1 per month ref ref ref ref ref ref
 1—3 times per month 3.9 (−6.8, 15.8) −2.8 (−15.6, 11.9) 6.4 (−12.6, 29.6) 9.2 (−6.5, 27.6) 1.2 (−12.6, 17.3) 0.6 (−21.8, 29.5)
 once per week −1.9 (−13.0, 10.6) −9.0 (−22.2, 6.4) 3.4 (−16.8, 28.6) 4.7 (−11.8, 24.4) 1.1 (−14.2, 19.0) −10.5 (−32.4, 18.3)
 ≥2 times per week 13.1 (−4.9, 34.4) 4.3 (−16.8, 30.7) −1.0 (−27.7, 35.6) 18.3 (−7.7, 51.6) 6.3 (−16.0, 34.6) 35.0 (−9.9, 102.2)
Time Spent Outdoors (In Summer)
 low ref ref ref ref ref ref
 medium 12.0 (−0.7, 26.4) 17.4 (0.3, 37.4) 17.1 (−6.0, 45.8) 13.0 (−4.9, 34.4) 18.1 (0.2, 39.2) 14.5 (−13.6, 51.7)
 high 14.5 (0.2, 30.9) 17.5 (−1.3, 39.9) 6.2 (−16.7, 35.3) 19.7 (−1.2, 45.0) 26.9 (5.8, 52.2) 29.5 (−5.2, 76.9)
Time Spent Outdoors (In Winter)
 low ref ref ref ref ref ref
 medium −1.7 (−10.8, 8.3) −4.4 (−15.8, 8.5) −15.0 (−28.8, 1.5) 2.8 (−10.6, 18.2) −7.5 (−19.0, 5.6) −13.9 (−31.4, 8.0)
 high −9.3 (−21.3, 4.4) −20.5 (−33.8, −4.4) −0.5 (−23.0, 28.6) −0.1 (−18.4, 22.2) −11.6 (−27.1, 7.1) −25.6 (−46.5, 3.4)
Maternal Characteristics
Age at Enrollment (per 5 years) −3.0 (−7.5, 1.7) −1.0 (−6.9, 5.3) −1.1 (−9.3, 7.8) −0.8 (−7.3, 6.2) −1.9 (−8.0, 4.7) 12.5 (0.7, 25.6)
Race/Ethnicity
 white ref ref ref ref ref ref
 black −26.0 (−34.7, −16.2) −27.4 (−38.3, −14.5) −36.2 (−49.2, −20.0) −3.7 (−19.5, 15.1) −6.9 (−21.5, 10.3) −32.7 (−49.7, −10.0)
 other −12.6 (−23.1, −0.8) −11.2 (−24.8, 4.8) −36.3 (−49.4, −19.8) 11.2 (−7.3, 33.4) −1.8 (−17.4, 16.7) −23.7 (−43.3, 2.6)
Education
 <college ref ref ref ref ref ref
 college 7.0 (−4.6, 20.0) 12.3 (−3.3, 30.4) 24.3 (0.9, 53.0) 10.3 (−6.4, 29.9) 6.2 (−9.2, 24.1) −13.9 (−31.4, 8.0)
Education
 >college 12.3 (−1.1, 27.5) 20.3 (1.8, 42.0) 38.2 (9.7, 74.2) 3.5 (−13.7, 24.3) 11.0 (− 6.6, 32.1) −25.6 (−46.5, 3.4)
Married or Cohabitating
 no ref ref ref ref ref ref
 yes 8.1 (−7.9, 26.9) 2.1 (−17.1, 25.8) −1.4 (−26.3, 31.8) −4.4 (−24.0, 20.2) 2.9 (−17.2, 28.0) −3.4 (−33.5, 40.4)
Parity
 0 ref ref ref ref ref ref
 ≥1 8.7 (−0.5, 18.7) 2.0 (−9.0, 14.5) −0.5 (−15.2, 16.8) 4.6 (−7.8, 18.7) 3.8 (−7.9, 17.1) 2.8 (−16.3, 26.3)
Household Characteristics
Annual Household Income
 ≤$40K ref ref ref ref ref ref
 $>40-≤70K −8.6 (−22.4, 7.7) 4.8 (−15.4, 29.8) −3.9 (−28.6, 29.5) 0.5 (−20.6, 27.1) 0.3 (−19.8, 25.4) 18.8 (−18.9, 74.2)
 $>70−≤150K −5.4 (−19.2, 10.7) −10.7 (−27.3, 9.6) −20.5 (−40.3, 5.8) 1.9 (−18.7, 27.8) −8.9 (−26.5, 13.0) −11.4 (−38.6, 27.9)
 >$1S0K −6.7 (−22, 11.5) −13.8 (−31.8, 8.9) −27.7 (−47.8, 0.1) 3.3 (−20.1, 33.6) −8.4 (−28.2, 16.9) −9.0 (−40.0, 38.2)
Carpeting or a Rug in Room Where Child Sleeps
 no ref ref ref ref ref ref
 yes 8.1 (−1.7, 18.8) 18.5 (4.8, 34.0) 14.5 (−3.5, 35.9) −0.2 (−12.9, 14.2) 10.0 (−3.2, 25.1) 23.8 (−0.6, 54.3)
Carpeting or a Rug in Room Where Child Spends Most Awake Time
 no ref ref ref ref ref ref
 yes −1.4 (−10.6, 8.7) −1.2 (−13.0, 12.2) 1.2 (−15.3, 20.7) −7.1 (−19.2, 6.8) −13.9 (−24.6, −1.7) −6.5 (−25.5, 17.3)
Neighborhood Characteristics
Census Tract Median Household Income (per $10,000 increase) 1.5 (−0.5, 3.6) 2.8 (0.2, 5.6) 0.7 (−2.9, 4.4) 0.9 (−2.0, 3.8) 4.1 (1.3, 7.0) 4.6 (−0.2, 9.6)
Model R2 0.25 0.22 0.19 0.05 0.08 0.16