Table 1.
Latent period of rats finding hidden platform in Morris water maze experiment (in seconds).
| Group | D3 (training) | D4 (SD 24 h) | D5 (SD 48 h) | D6 (SD 72 h) | D7 (SD 96 h) | D8 (SD 120 h) |
|---|---|---|---|---|---|---|
| N | 114.67 ± 9.39 | 80.76 ± 37.69 | 55.68 ± 31.41 | 32.05 ± 17.70 | 23.07 ± 13.12 | 13.80 ± 8.02 |
| NGS | 113.71 ± 11.01 | 83.26 ± 33.58 | 57.66 ± 22.88 | 33.40 ± 22.12 | 24.33 ± 19.39 | 14.07 ± 9.86 |
| WP | 115.18 ± 5.79 | 86.54 ± 19.75 | 57.73 ± 35.76 | 35.52 ± 15.90 | 29.78 ± 22.17 | 19.15 ± 11.78 |
| M | 112.66 ± 10.70 | 94.73 ± 29.35 | 70.53 ± 26.47 | 48.53 ± 25.96 | 34.40 ± 14.74∗ | 26.23 ± 15.21∗∗ |
| MGS | 111.23 ± 9.45 | 86.93 ± 24.68 | 57.82 ± 33.55 | 41.90 ± 19.80 | 28.41 ± 17.17 | 20.93 ± 11.57 |
From experimental day 3 to day 8 (the whole SD period), all rats received 2 times learning trials with 30 min interval in MWM. N: normal control rats; NGS: normal control rats with total ginsenoside (GS) intervention; WP: normal control rats housed on wide platform; M: SD model; MGS: SD model with GS intervention. Normal, WP, and model groups received normal saline solution; NGS and MGS received GS orally at a daily dose of 100 mg/kg of body weight from day 1 to day 8. Data were expressed as the latent time (seconds) for each rat finding the hidden platform in test trials, shown as mean ± SD. ∗P < 0.05 and ∗∗P < 0.01, compared to the N group (n = 8).