Table 1.
T-cell lymphoma subtype | No. (%) | |||
---|---|---|---|---|
Cyclin D1 | Cyclin D2 | Cyclin D3 | pStat3 | |
Anaplastic large cell lymphoma, ALK+ | 8/34 (24%) | 10/12 (83%) | 12/12 (100%) | 13/13 (100%) |
Anaplastic large cell lymphoma, ALK- | 3/44 (7%) | 7/15 (47%) | 5/15 (33%) | 6/16 (38%) |
Peripheral T-cell lymphoma, NOS | 3/68 (4%) | |||
Angioimmunoblastic T-cell lymphoma | 0/24 (0%) | |||
Extranodal NK/T-cell lymphoma, nasal type | 0/7 (0%) | |||
Enteropathy associated T-cell lymphoma | 0/4 (0%) | |||
Hepatosplenic T-cell lymphoma | 0/3 (0%) | |||
Cutaneous anaplastic large cell lymphoma | 0/5 (0%) | |||
Mycosis fungoides | 0/5 (0%) | |||
Subcutaneous panniculitis-like T-cell lymphoma | 0/1 (0%) | |||
CD4-positive pleomorphic T-cell lymphoma | 0/1 (0%) | |||
T-cell large granular lymphocytic leukemia | 0/4 (0%) | |||
Overall | 14/200 (7%) |
p value between ALCL, ALK+ and ALCL, ALK-negative for cyclin D1 (p=0.05), cyclin D2 (p=0.28), cyclin D3 (p=0.03), and pSTAT3 (p=0.039)